This study is designed to evaluate the safety, tolerability, and effectiveness of OT-101 when used in combination with standard of care (SoC) in hospitalized COVID-19 patients. OT-101 is a wide spectrum anti-viral agent with demonstrated activity against SARS-CoV-2 in the nanomolar range comparable to remdesivir, however, with higher safety index. By targeting the host protein, TGF-β, OT-101 avoids resistance mutations which could render vaccine and/or therapeutics against viral protein(s) ineffective.
For more information and how to get involved about the C001 study, visit sponsor website here.
Mateon was created by the recent reverse merger with Oncotelic which became a wholly owned subsidiary of
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Source: Mateon Therapeutics, Inc.